"Inside Out 2" appears to pick up where the original film left off with Riley entering her teenage years at the age of 13.
The well-known emotions of Joy (voiced by Amy Poehler), Sadness (voiced by Phyllis Smith), Anger (voiced by Lewis Black), Fear and Disgust are still part of the cast, although Bill Hader and Mindy Kaling are not voicing Fear and Disgust anymore.
A significant change is introduced in Riley's emotional world as a construction crew enters her headspace announcing "demolition day."
This development leads to her original emotions seeking cover nervously.
Mann explains that Anxiety, while new to the crew is not one to take a back seat. This character's inclusion makes sense when considering the complexities of the human mind.